Drug Standards
Apexbio Technology LLC Fexofenadine HCl 153439-40-8 50mg
Fexofenadine HCl (CAS 153439-40-8) is a non-sedating antihistamine that selectively antagonizes the histamine H1 receptor It inhibits H1 receptor-mediated signaling with an IC50 of 246 nM indicating potent receptor binding in vitro Fexofenadine is employed in biomedical research to investigate histaminergic pathways allergic responses and receptor pharmacology facilitating the study of H1 receptor antagonism in cellular and molecular models
Apexbio Technology LLC Ketoconazole 65277-42-1 500mg
Ketoconazole (65277-42-1) is a small-molecule inhibitor targeting cytochrome P450-dependent enzymes including cyclosporine oxidase and testosterone 6 -hydroxylase It is designed to inhibit these catalytic activities thereby modulating the oxidative metabolism of clinically relevant substrates Ketoconazole exerts its biological activity primarily through inhibition of cytochrome P450-mediated pathways In in vitro studies ketoconazole demonstrates inhibitory activity with an IC50 of approximately 0 19 mM for cyclosporine oxidase and about 0 22 mM for testosterone 6 -hydroxylase Based on these pharmacological properties ketoconazole holds research potential in studies of drug-drug interactions hepatic enzyme induction and metabolic profiling assays
Selleck Chemical LLC Hydroxychloroquine Sulfate 50mg 747-36-4 HCQ
Hydroxychloroquine Sulfate (HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Ebselen (25mg). CAS: 60940-34-3
Organoselenium compound. Antioxidant. Selenium-based inhibitor of protein kinase C, NADPH, 5-lipoxygenase, cyclooxygenase (COX) and NADPH oxidase. Anti-inflammatory antioxidant. Mimics glutathione peroxidase. Inhibits oxidative modifications of low density lipoproteins (LDL). Protects cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death. Formula: C13H9NOSe. MW: 274.2. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO or 100% ethanol. Long Term Storage: -20°C. Handling: Protect from light.
Selleck Chemical LLC Copanlisib (BAY 80-6946) 5mg 1032568-63-0
Copanlisib (BAY 80-6946) is a potent pan-class I PI3K with IC50 of 0.5, 3.7, 6.4, and 0.7 nM in cell-free assays for PI3K?/?/?/? , respectively. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC LY2584702 Tosylate
LY2584702 Tosylate is a selective ATP-competitive p70S6K inhibitor with IC50 of 4 nM Phase 1
Medchemexpress LLC Voriconazole impurity 1 | 137330-52-0 | ≥98.0% | C16H14F3N5O | 50 MG
Voriconazole impurity 1 is a chemical compound that serves as an impurity of Voriconazole. It has a molecular weight of 349.31 and a chemical formula of C16H14F3N5O. This solid substance has a purity of ≥98.0% and is intended for research use only.
- Suitable for research applications
- Purity of ≥98.0%
- Solid appearance
- Store at 4°C in sealed, moisture-free conditions
- When in solvent, store at -80°C for 6 months or -20°C for 1 month
Selleck Chemical LLC LY2584702 Tosylate
LY2584702 Tosylate is a selective ATP-competitive p70S6K inhibitor with IC50 of 4 nM Phase 1
Medchemexpress LLC Moxifloxacin-d3-1 hydrochloride | 1246816-75-0 | C21H22D3ClFN3O4 | 500 UG
Moxifloxacin-d3-1 hydrochloride | 1246816-75-0 | C21H22D3ClFN3O4 | 500 UG
Apexbio Technology LLC Nitisinone 104206-65-7 10mg
Nitisinone (CAS 104206-65-7) is a synthetic small molecule that selectively inhibits 4-hydroxyphenylpyruvate dioxygenase an enzyme involved in the catabolic pathway of tyrosine By blocking this enzyme nitisinone disrupts the conversion of 4-hydroxyphenylpyruvate to homogentisic acid leading to reduced production of toxic tyrosine metabolites This mechanism is utilized in studies of hereditary tyrosinemia type 1 where nitisinone serves as a pharmacological tool to investigate metabolic regulation and therapeutic intervention in tyrosine degradation disorders
Selleck Chemical LLC Benzalkonium chloride
Benzalkonium chloride a detergent and preservative found in health care and household products is an established irritant
U.S. Pharmacopeia acetazolamide | 59-66-5 | 222.3 g/mol | 2G
acetazolamide | 59-66-5 | 222.3 g/mol | 2G
TARGETMOL CHEMICALS INC Tenofovir Disoproxil 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Purity 99.17%
Selleck Chemical LLC Amiloride HCl 50mg 2016-88-8
Amiloride is a selective T-type calcium channel blocker, an epithelial sodium channel blocker and a selective inhibitor of urokinase plasminogen activator (uPA)(Ki=7 ?M). *For Research & Development use only. Product is not intended for drug, household, or human consumption.